When fewer nutrients get in

Step 4: Fewer nutrients get in

We've followed the loop from struggling mitochondria, to spent antioxidants, to oxidized membranes.

Here's the next link. The cell membrane isn't just a wall. It's the gatekeeper, with channels and receptors that let nutrients in and signals through. When the membrane is damaged, those doors can work less well.

So a cell can be surrounded by what it needs and still not get enough. That's step 4, and it's how the loop can feed itself: less fuel getting in means mitochondria struggle more.

In your labs

Labs that offer a clue:

Cholesterol and triglycerides. Healthy cholesterol along with low triglycerides often goes with healthy cell membranes and good fat handling. High triglycerides can point to the opposite.
Magnesium. It's needed for hundreds of reactions, including making energy. Note that a standard serum magnesium test can look normal even when cells are low, so symptoms and context matter.

Read about niacin and triglycerides →Read about magnesium →

Next, in Part 5: How the immune system responds to all this damage, and why inflammation can rise.

Educational information only — not medical advice. Lab testing and any supplementation decisions should be made with a qualified healthcare provider who knows your personal health history. Research findings vary by population, dose, form, and study quality.

Some links go to Fullscript, where I may earn a commission at no extra cost to you. I only recommend supplements I've either used myself or seen work in my clients' lab data. Results vary from person to person.